Herbs have an impact on your dog's health, but is it Science proven ? Have a look.

Our Ingredients: Proven by studies (peer-reviewed)

At Lupo's Life, we focus on verifiable quality and effectiveness. Our formulation is based on scientific findings. Here you will find some selected studies that prove our active ingredients and their health benefits. Some examples:

• Echinacea: In this clinical study, the oral administration of an Echinacea purpurea extract led to a significant stimulation of the immune system in dogs. After 60 days of supplementation, the echinacea dogs showed significantly higher red and white blood cell counts (including lymphocytes and neutrophils) and an increase in IgM levels in the blood. The phagocytosis activity of the immune cells was also increased. These results show that echinacea can strengthen the non-specific immune system in dogs - dogs develop an improved immune response and are therefore better able to fight off infections.Source: Evaluating the effect of oral administration of Echinacea hydroethanolic extract on the immune system in dog - PubMed
  
  
• Collagen: Osteoarthritis (OA) is the most common joint disorder in humans and dogs. Due to its chronic progressive nature, the predominant clinical signs after a certain point are pain and immobility. 
  Source: The oral intake of specific Bioactive Collagen Peptides (BCP) improves gait and quality of life in canine osteoarthritis patients—A translational large animal model for a nutritional therapy option - PMC
  
  
• Spirulina: Supplementing diets with Spirulina resulted in significantly increased gut microbiota stability in the test group. In conclusion, diets supplemented with Spirulina significantly enhanced immune response and gut health in dogs.
  Source: Supplementation of Diets With Spirulina Influences Immune and Gut Function in Dogs - PubMed
  
  
• Curcuma/Turmeric: A promising solution for pets with osteoarthritis is turmeric, as study after study keep showing. Most recently, one study¹ showed that dogs that are fed turmeric had significantly fewer inflammatory blood cells than dogs treated with painkillers (NSAIDS).
  Source: Turmeric for osteoarthritis – a spice that has convinced scientists
  
  
• Rosehip/Willow bark/Nettle: In this in vitro study on canine joint cells, rosehip extracts showed strong anti-inflammatory effects. The addition of rose root (Rosa canina) suppressed the NF-κB signaling cascade activated by inflammatory stimuli (IL-1β) and significantly reduced the expression of inflammatory enzymes (COX-2, MMP-9). At the same time, the degradation of cartilage matrix components was slowed down and their regeneration promoted. These results indicate that rose hips can inhibit joint inflammation and protect articular cartilage through their antioxidants and polyphenols. 
  Source: Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB Activation in Canine Articular Chondrocytes - PMC
  
  
• Milk Thistle:  Milk thistle, Silybum marianum, is a medicinal plant grown for its bioactive compounds with well-documented antioxidant and hepatoprotective properties. Milk thistle has a well-established pharmacological reputation for treatments of human liver disease, but it is also used in animals. The overall picture shows that the use of milk thistle results in improved or restored health parameters or better animal performance. 
  Source: Use of Milk Thistle in Farm and Companion Animals: A Review - PubMed
  
  Please pay attention to how your canine reacts to our nutrients, as of course there can always be some intolerance to certain ingredients. Discontinue the food supplement immediately and contact your veterinarian in the event of any adverse reaction.